Each and every mobile unit is equipped with a state of the art 3D PET system and CardioGen-82, the Rubidium-82 generator.
The Rubidium-82 generator, CardioGen-82, is a closed system that produces the radiotracer for intravenous administration. CardioGen-82 includes a self-contained cart that houses a shield for the generator, on-board support for electronics, and a waste container. The infusion tubing system is automated for the infusion and accurate patient dosage with minimal operator interface. In addition, the system is lead lined and weighs 650 pounds. This combination creates the least amount of radiation exposure possible to your patient, as well as our nuclear medicine technologists.
The CardioGen-82 is the only BRACCO-certified generator that has an FDA-approved Rubidium-82 generator-based perfusion agent available for cardiac PET. The isotope is produced on a per need basis, and the generator is replaced every 28 days, both in compliance with the regulations regarding radioactive material dictated by the United States Nuclear Regulatory Commission.
Rubidium-82 generator is a positron emitting radiotracer with a physical half-life of 75 seconds. Following intravenous administration, the 20mCi dose of Rb-82 is rapidly taken up by the heart muscle. The isotope activity is noted in the heart within the first minute after injection. The 3D PET system takes 3D images of Rb-82 uptake by the heart. The patient is then administered Lexiscan, a pharmacological stress agent, and the procedure is repeated. Further analysis of these images helps to identify the location, severity and extent of reduced blood flow to the heart muscle (ischaemia).
Myocardial perfusion imaging with Rubidium-82 is quickly becoming the diagnostic tool of choice in nuclear medicine. The short half-life of Rb-82 leaves the patient with minimal radiation exposure, and the scan time is only 25-35 minutes. The increased benefits over comparable isotopes also include availability around the clock, excellent image quality regardless of patient body habitus, higher diagnostic accuracy, reduced occupational radiation exposure to staff, and the ability to image peak stress left ventricular function.
For a detailed look at the advantages of Rb-82 generator cardiac imaging, click here.