Case Study 3

Patient History

Patient is a 77-year-old female who presented with atypical chest pain. Past medical history includes hypertension. ECG shows normal sinus rhythm and nonspecific T-wave abnormalities. Patient’s medication chart included Atenolol, Famotidine, Aspirin, and Lovenox®. Time between SPECT and Cardiac PET exam was 14 days.

Body Habitus

Height: 5’1”
Weight: 160lbs
BMI: 31 Kg/m2

SPECT Images

PET Images

Protocol Characteristics
Protocol SPECT PET
Mode of Stress Adenosine (4 minutes) Dipyridamole (4 minutes)
Clinical Response Non-ischemic Non-ischemic
Blood Pressure Response Normal Normal
ECG Response Negative Negative
Radiopharmaceutical Tc-99m Sestamibi Rubidium-82
Rest/Stress Dose 11mCi/33mCi 60mCi/60mCi
Gated Yes Yes
Length of Exam Time 2.5 hours 40 minutes



Since the SPECT images shown here could not be read with confidence, the patient was subsequently referred for a PET scan.

PET MPI Report

The PET images demonstrated normal myocardial perfusion with interpretive certainty.

Note: Cardiac catheterization was not performed because the PET MPI study was normal.

Reference: Case study courtesy of Medical Imaging & Technology Alliance ( The report was prepared by Dr. Marcelo DiCarli at Harvard/Brigham & Women’s Hospital in Boston, MA.

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